Abstract
Reaction of ZnCl 2 with a new ligand N, N-bis(3,5-dimethylpyrazolylmethyl)- l-alaninemethylester (bdmpame) in methanol gives [ZnCl 2(bdmpame)]. The structure of [ZnCl 2(bdmpame)]·CH 2Cl 2 has been resolved by X-ray crystallographic analysis. The Zn atom has a distorted tetrahedral geometry involving a nitrogen atom from each pyrazole in bdmpame and two chloro ligands with bond lengths in the range 2.037(4)–2.237(2) Å. The nitrogen atom of the l-alaninemethylester group in the compound was not coordinated to the metal center, giving an eight-membered ring in which the nitrogen atoms of each pyrazole in bdmpame are coordinated to the metal center. The results of the catalytic enantioselective reduction of acetophenone promoted by ligand/Zn(OTf) 2=1:1 mole ratio in the presence of catecholborane for 48 h at 0°C gives ( S)-(−)-1-phenylethanol in 21% ee with 68% yield.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
