Abstract
A series of oxadiazole incorporated ellipticine derivatives were synthesized and evaluated for their anticancer activity on human cancer cell lines Colo-205, MCF-7, A-549, and KB. Five of the newly synthesized target products exhibited potent cytotoxic activities with GI50 values ranging from <0.1 to 23.6 µM, where the positive control etoposide showed GI50 values ranging from 0.13 to 3.08 µM.
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Schedule a callMore From: Monatshefte für Chemie und verwandte Teile anderer Wissenschaften
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