Abstract

A general method was developed for the synthesis of novel unsymmetrical 3, 5-disubstituted 4H-1, 2, 4-triazoles with benzyl group in the 4-ring position (5a-j). A series of novel N-acyl amidrazone derivatives (4a-j) have been synthesized. The chemical structures of newly synthesis zed compounds were characterized by IR, H 1 NMR,C 13 NMR and mass. The newly synthesized compounds were screened for antimicrobial activity.

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