Abstract
A Schiff base has been prepared by the reaction of 4-acetyl-5-methyl-2-(4-methylphenyl)-2,4-dihydro-3 H -pyrazole-3-one with different substituted amines. Treatment of this Schiff base with chlorobactyl chloride affords the corresponding azetidinone in good yield. All the new compounds have been characterized by IR, 1 H NMR, GC-MS and elemental analysis. The antibacterial activity of these compounds has been determined with the reference of standard drug.
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