Abstract

Abstract The Schiff base N,N′-bis(salicylidene)thiourea and its complexes of copper(II), nickel(II) and zinc(II) have been synthesized and characterized by elemental analyses, molar conductivity measurements, thermal analyses, infrared and electronic spectral data. The Schiff base ligand has been further identified by 1H NMR and mass spectra. The results suggest that the Schiff base behaves as a quadridentate ligand attached to the metal ion through the phenol oxygen and imino nitrogen atoms. The biological activities of these compounds to scavenge superoxide free radicals and poison Oncomelania hupensis (a kind of an intermediate host of blood fluke) are also reported.

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