Abstract

The N-Functionalization of the daunorubicin amino group allows for introducing different functional and pharmacophore groups into the anthracycline core. Herein, the possibility of introduction of a benzo[d][1,3]dioxol-5-yl moiety and its derivatives into the structure of the initial moiety is demonstrated by the examples of four new anthracyclines. The biological activity of the resulting compounds is explored.

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