Abstract

Previously undescribed esters based on N-substituted imides of cycloaliphatic carboxylic acids have been synthesized in high yields and efficient methods for their preparation have been presented. Toxicological studies of the obtained compounds were carried out using various test objects (Chlorella vulgaris, Allium cepa, Drosophila melanogaster). It was shown that the studied compounds are not active against D. melanogaster, increase the frequency of mutations in C. vulgaris and have the ability to induce chromosomal rearrangements in A. cepa. The synthesized compounds can be used in the development of antitumor drugs.

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