Abstract
A series of 1-(4-substituted phenyl)-1-alkyl-2-phenyl-3-morpholinopropanols (I) have been synthesized via the interaction of 4-substituted α-phenyl-β-morpholinopropiophenones with Grignard's reagents in ether. The antiinflammatory and analgesic (non-narcotic) properties of the synthesized compounds have been evaluated. The most pronounced analgesic (non-narcotic) activity was observed for aminopropanols with 1-isoalkyl (isopropyl, isobutyl, isoamyl) radicals.
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