Abstract
Two 5β-hydroxy analogs of α-ecdysone — 2β,3β,5β,14α-tetrahydroxy-5β-cholest-7-en-6-one and 3β,5β,14α-trihydroxy-5β-cholest-7-en-6-one were synthesized and their mass spectra obtained. The biological activity of these two compounds was compared with that of the most active synthetic ecdysone analog previously tested in insects, and the presence of the 5β-hydroxyl group generally enhanced the inhibitive activity.
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