Abstract

By alkylation of 4-fluorophenylacetonitrile with dibrompеntane and 2.2-dichlor-diethylether the corresponding nitriles were obtained, with which reduction by lithium aluminium hydride [1-(4-fluorophenyl)cyclohexyl]- and [1-(4-fluorophenyl)tetrahydro-2 H -pyran-4-yl]methanamines were isolated. By the reaction of the latters with substituted in aromatic cycles aryloxymethyloxiranes new aryloxypropanolamines were been synthesized. Some of them by the action of formaline were transformed to the corresponding oxazolidines.

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