Abstract

A series of peptides with N 3-( S)-bromosuccinamoyl-( S)-2,3-diaminopropanoic acid, a novel selective inhibitor of glucosamine-6-phosphate synthase were synthesized and evaluated in vitro for antimicrobial activity against selected bacterial and fungal strains including dermatophytes. All the peptides were found to be active against a broad range of bacteria and fungi. Tripeptides exhibited remarkable anticandidal activity.

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