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Abstract
Synthesis and antimicrobial evaluation of some typical macrocyclic crown ethers including amide, sulfonamide, and disulfide moieties are reported. Novel macrocyclic bis -sulfonamide, amide, and disulfides are prepared by reacting the bis -chlorides and diamines by fast addition method. The antimicrobial activities of the synthesized compounds are measured. Bis -sulfonamide and disulfide crown ethers showed antibacterial activities against most strains tested.
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