Abstract
New series of thiazole derivatives were synthesized using 5-(aryldiazo)salicylaldehyde thiosemicarbazones 2a–i. Cyclocondensation of thiosemicarbazones 2a–i with chloroacetone afforded the corresponding 4-methylthiazole derivatives 3a–i. Moreover, cycloalkylation of 2a–i with ethyl bromoacetate afforded the corresponding thiazolidin-4-one derivatives 4a–i. The antimicrobial activity of the new thiazole derivatives was evaluated.
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