Abstract
In this study, some aryl naphtho[2,1-b]furan-2-yl ketoximes and their ethers and esters were synthesised. The structure elucidation of the compounds was performed by IR, 1H-NMR and MASS spectroscopic data and elemental analyses results. Antifungal activities of the compounds were tested against Candida albicans (two strains), Candida glabrata, Candida tropicalis and Candida parapsilosis using a microbroth dilution technique. The results showed that the compounds displayed minimum inhibitory concentrations, 7.8-625 µ g/mL. Keywords: Aryl naphthofuran ketoximes, Aryl naphthofuran O-methylketoximes, Aryl naphthofuran ketoxime acetates, Antifungal activity, Antifungal activities, Candida albicans, Candida glabrata, naphtho[2,1-b]furan-2-yl ketoximes, azole, oxime, diaryl ketoximes, benzofuran-2-yl ketoxime, tetramethylsilane (TMS), Reimer-Tiemann reaction procedure
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.