Abstract
Synthesis and antibacterial activity of epoxide from hyptolide (Hyptis pectinata (L.) Poit) against Gram-positive and Gram-negative bacteria
Highlights
Hyptis pectinata (L.) Poit is a family Lamiaceae plant that can be found in tropical areas such as Brazil, Mexico, India, and Indonesia
This study aimed to investigate the relationship between hyptolide and its epoxide structure on the antibacterial activity against Gram-positive and Gram-negative bacteria
The purpose of this research was to evaluate the relationship between the structure of hyptolide and its epoxy hyptolide transformation and the antibacterial activity of Grampositive and Gram-negative bacteria strains
Summary
Hyptis pectinata (L.) Poit is a family Lamiaceae plant that can be found in tropical areas such as Brazil, Mexico, India, and Indonesia. The activity of the transformation structure of hyptolide has never been explored, whereas previous research explained that the functional group has a crucial role in the activity Among these properties are antimicrobial activities exhibited by the epoxide structure of the compound (Husain and Shaharyar, 2015). Other studies explained that the oxirane ring in the epoxide structure has an important role as antibacterial (Thirunarayanan and Vanangamudi, 2016) Based on these data, in this study, we evaluated the relationship between the structure of hyptolide and its transformation of epoxy hyptolide in the antimicrobial activity against Gram-positive and Gram-negative bacteria
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