Abstract
Six new random copolyesters with ethereal linkages were prepared from a potential mesogenic non-linear monomer 4, 4'-oxybis(benzoic acid) by direct poly-condensation with different aliphatic and aromatic diols in pyridine solution. Diphenylchlorophosphate (DPCP) was employed as the condensation agent. Viscosity measurements, FTIR, 1 H and 13 C NMR spectral data were used for investigating their structural features. The thermal phase transition behavior of these polymers was investigated by Differential Scanning Calorimetry (DSC). Agar well diffusion method was employed to study the antibacterial activity of these random copolyesters. All the six random copolyesters showed significant inhibition against the test bacteria. The presence of ether group in the main chain of the polyester enhances the solubility in organic solvents and hence eases processing.
Highlights
IntroductionBy incorporating biologically active organic Carolina and fellow researchers has developed polymer moieties into the polymer backbone, the activities can be coatings that prevent bacteria sticking to implant introduced
The aim of this study was to prepare random copolyesters and its antibacterial potential was evaluated with pathogenic bacteria
The antibacterial activity of all the random copolyesters derived from 4,4′-oxybis(benzoicacid) is high, which could be due to the presence of ether linkage in the oxybis(phenylene) moiety
Summary
By incorporating biologically active organic Carolina and fellow researchers has developed polymer moieties into the polymer backbone, the activities can be coatings that prevent bacteria sticking to implant introduced. In terms of their biological activity, these surfaces. University of Washington researchers drug-delivering agents to deliver drugs directly to the Horbett et al (1999) have developed a method of crafting intended site of action and can improve efficacy medical implants from an antibacterial polymer that could while minimizing unwanted side effects elsewhere in the prevent thousands of patients from dying of hospitalbody which often limit the long term use of the drugs. Chitra and coworkers (2010) reported the investigated their antimicrobial activity against bacteria. bactericidal activity of certain copolyesters containing
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