Abstract
Our previous work identified various novel Chalcones (I-III) produced by mixing the equimolar amount of Ferrocene aldehyde and different substituted acetophenones which has a strong base. Hence, in the present study, novel various Chalcones (I-III) were treated with hydroxylamine hydrochloride to form various Isoxazoles (Ic-IIIc). The synthesized novel chalcone-based Isoxazole derivatives were determined by spectroscopic techniques such as1H,13C-NMR, FT-IR,and UV. Further, these products were evaluated for antimicrobial studies and antioxidant susceptibilities through DPPH radical scavenging method. The synthesized isoxazole (Ic) was subjected to a study of their anti-inflammatory activity(COX and LOX) assay.
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