Abstract

Macroporous poly(vinyl acetate-co-triallyl isocyanurate) beads were prepared with suspension polymerization method. The copolymer beads were transformed into poly(vinyl alcohol-co-triallyl isocyanurate) by ester exchange reaction. Epoxy group was than connected to the surface of poly (vinyl alcohol-co-triallyl isocyanurate) by the reaction of epichlorohydrin with the hydroxyl group of the copolymer. And carboxyl groups were immobilized through 1,6-hexanediamine or triethylenetetramine space arm or directly connected to the hydroxyl group on the copolymer beads. The blood compatibility and adsorption properties for low density lipoprotein (LDL) in human plasma of the resultant macroporous crosslinked PVA-based adsorbents were investigated.

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