Abstract
8-Amino-1, 2, 3, 4-tetrahydro-7-methoxy-1-(4-methoxybenzyl)-2-methyl-6-isoquinolinol (IIa) was synthesized and the Pschorr reaction of this compound under alkaline conditions gave dl-homolinearisine, which could not be synthesized by the phenolic oxidative coupling method. Infrared and nuclear magnetic resonance spectra of the synthesized sample were superimposable with those of the natural product.
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