Abstract
Four new copper(II) complexes, [CuL1(?1,1-N3)]n (1), [CuL1(?1,3-NCS)]n (2), [Cu(HL2)2](SCN)2 (3) and [Cu(L2)2] (4), where L1 and L2 are 2-((2-(dimethylamino)ethylimino)methyl-4,6-difluorophenolate and 2,4-difluoro-6-((3-morpholinopropylimino) methyl)phenolate, respectively, and HL2 is 2-((2-(dimethylammonio)ethylimino)methyl-4,6-difluorophenolate, were synthesized and characterized by elemental analysis, IR and UV-vis spectroscopy. The structures for the complexes were further confirmed by single crystal X-ray structure determination. Complexes 1 and 2 are polymeric copper(II) complexes, with the Cu atoms in square pyramidal coordination. Complexes 3 and 4 are mononuclear copper(II) complexes, with the Cu atoms in square planar coordination. The complexes were assayed for their antimicrobial properties.
Highlights
The complexes were readily prepared by the reaction of equimolar quantities of 3,5-difluorosalicylaldehyde, N,N-dimethylethane-1,2-diamine or N-(3-aminopropyl)morpholine, sodium azide or ammonium thiocyanate, and copper bromide in methanol
The Cu atom is coordinated in a square pyramidal geometry, with the phenolate O1, imino N1, amino N2 atoms of the Schiff base ligand L1, and the azido N3 atom defining the basal plane, and with the azido N3A atom located at the apical position
The Cu atom is coordinated in a square pyramidal geometry, with the phenolate O1, imino N1, amino N2 atoms of the Schiff base ligand L1, and the thio
Summary
Schiff base compounds and their metal complexes have attracted much attention due to their interesting biological aspects like antibacterial, antifungal, and antitumor.. It has been proved that the compounds with electron-withdrawing substituent groups can enhance their antimicrobial ability.. Rai et al reported some compounds with fluoro, chloro, bromo, and iodo-substituted groups, and their remarkable antimicrobial property.. Schiff base complexes of copper have potential antibacterial property.. Our research group has reported some Schiff base complexes with biological properties.. In pursuit of new Schiff base complexes with potential antimicrobial property, in this work, four new copper(II) complexes, [CuL1(μ1,1-N3)]n [1], [CuL1(μ1,3-NCS)]n [2], [Cu(HL2)2] (SCN)2 [3] and [Cu(L2)2] [4], where L1 and L2 are 2-((2-(dimethylamino)ethylimino)methyl-4,6-diluorophenolate and 2,4-difluoro-6-((3-morpholinopropylimino)methyl) phenolate, respectively, and HL2 is 2-((2-(dimethylammonio)ethylimino)methyl-4,6-diluorophenolate, and their antimicrobial properties are present
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