Syntheses, Crystal Structures and Antimicrobial Activity of Copper(II) Complexes with the Ligand N,N'-Bis(4-bromosalicylidene)propane-1,2-diamine.

Abstract

Three new copper(II) complexes, [CuClL] (1), [CuBrL]n (2) and [CuL(NCS)]n (3), derived from the Schiff base 2,4-dichloro-6-((2-pyrrolidin-1-ylethylimino)methyl)phenol (HL) have been prepared and characterized by spectroscopy methods, as well as single crystal X-ray determination. The Cu atom in complex 1 is in square planar coordination, and those in complexes 2 and 3 are in square pyramidal coordination. The Schiff base ligand coordinates to the Cu atoms through phenolate oxygen, imino nitrogen and pyrrolidine nitrogen. The antibacterial activities of the Schiff base and the three copper complexes have been assayed on the bacteria Staphylococcus aureus and Escherichia coli, and the yeast Candida parapsilosis.