Abstract
Abstract Pyrophosphate tetraesters possessing allylic and homoallylic side chains were synthesized. Reaction of alkyl allyl (and 3-methyl-3-butenyl) phosphorochloridates with sodium hydrogencarbonate gave P1,P2-dialkyl P1,P2-diallyl [and P1,P2-bis(3-methyl-3-butenyl)] pyrophosphates. Condensation of alkyl allyl (and 3-methyl-3-butenyl) phosphorochloridates with dialkyl phosphates gave trialkyl allyl (and 3-methyl-3-butenyl) pyrophosphates. Reactions of crotyl (2-butenyl) pyrophosphates with various nucleophiles such as phenolic ethers, aromatic amines, and nitrogen-containing heterocycles in the presence of boron trifluoride etherate gave good to moderate yields of crotylated products. The crotyl pyrophosphates were found to be much more reactive than the corresponding orthophosphate esters.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
