Abstract
A review dealing with iminosugars as inhibitors of α-L-fucosidases is presented. The different synthetic approaches for the preparation of the most relevant ones as well as their inhibitory properties are presented. Keywords: Azafagomines, hydroxylated azepanes, piperidines, pyrrolidines, fucosidase inhibitors, iminosugars, azasugars, L-Fucosidase Inhibitors, glycosylation, glycosylation reactions, hydrolysis, glycoconjugates, carcinomas, L-fucosidases, Thermotoga maritima, Thermotoga maritima enzyme, iminocyclitols, hydrophobic, POLYHYDROXYLATED PYRROLIDINES, meso-pyrrolidine 1, human placenta, chromatography, Holzapfel, Crous method, Oxime, Bayon's method, pyrrolidinethylphosphonate, nitrone, Cope-House cyclization, tetraacetate, POLYHYDROXYLATED PIPERIDINES, POLYHYDROXYHEXAHYDROPYRIDAZINES, POLYHYDROXYAZEPANES
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