Synthese eines 2,5,7,10‐substituierten 1,6‐Methano[10]annulens, seine Methylierung, Ätherspaltung und Deprotonierung

Abstract

AbstractSynthesis of a 2,5,7,10‐Substituted 1,6‐Methanol[10]annulene, its Methylation, Ether Cleavage; and DeprotonationThe synthesis of 2,7 ‐di(tert ‐butoxy)‐1,6‐methanol[10]annulene derivatives 2 and 3 are described. Methylation of 3 gave 4, and 4 was transformed, on treatment with p‐toluene sulfonic acid, to the salt 5. Basic reagents deprotonated 5; the resulting solution was analyzed by 1H‐NMR spectroscopy.