SYNTAX score effect on electroencephalography power dynamics in patients undergoing on-pump coronary artery bypass grafting

Irina V Tarasova,Olga L Barbarash,Leonid S Barbarash,Roman S Tarasov,Olga A Trubnikova

doi:10.1186/1471-2202-14-95

Abstract

BackgroundThe severity of angiographically assessed coronary artery disease may be the factor that influences the degree of brain damage during on-pump surgery. Modern technology such as computed electroencephalography (EEG) that is used to detect signs of brain damage could also be used to determine the advantages and disadvantages of various surgical myocardial revascularization methods in certain categories of patients. The present study investigated EEG power dynamics for 1 postoperative month in patients undergoing on-pump coronary artery bypass grafting (CABG) who were divided into two groups: those with moderate coronary lesions (SYNTAX score ≤ 22, n = 12) and those with severe coronary lesions (SYNTAX score ≥ 23, n = 18).ResultsAt 7–10 days after CABG, all patients showed theta type 1 rhythm power higher than that seen preoperatively, possibly indicating that brain damage occurred during bypass. At 1 month after CABG, the theta type 1 rhythm power had decreased to the baseline level in patients with SYNTAX scores of ≤22, whereas it had increased in patients with SYNTAX scores ≥23.ConclusionsSYNTAX scores ≥ 23 are associated with EEG markers of perioperative brain damage during CABG. Careful preoperative assessment, preparation, and more effective intraoperative brain protection are essential for this category of coronary heart disease (CHD) patients.

Highlights

The severity of angiographically assessed coronary artery disease may be the factor that influences the degree of brain damage during on-pump surgery
In patients with SYNTAX scores ≤ 22, the ejection fraction (EF) decreased from 59.9 ± 5.11% to 52.6 ± 6.56% (p = 0.003), and in those with SYNTAX scores ≥23 it decreased from 56.1 ± 12.15% to
A high SYNTAX score is associated with EEG markers of brain damage after on-pump coronary artery bypass grafting (CABG) at the 1-month follow-up

Summary

Introduction

The severity of angiographically assessed coronary artery disease may be the factor that influences the degree of brain damage during on-pump surgery. The duration of cardiopulmonary bypass (CPB), manipulation of the aorta, and the effects of anesthesia have been suggested as causative factors in the development of cerebral ischemia during on-pump surgery. Preoperative factors, such as a high functional class of heart. There are a number of scales that can objectively evaluate the complexity of coronary artery disease on the basis of angiographic data (SYNTAX score) or combined clinical and angiographic data The latter include the Functional SYNTAX score, the New Risk Classification (NERS), and the Clinical SYNTAX score (CSS) [5-7].

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