Abstract
Purpose: Independent of age-related changes, superoxide dismutase (SOD) activity in cartilage was reported to be low in end-stage osteoarthritis (OA). However, the role of SOD in the synovium, which is strongly involved in OA pathology, remains unclear. In this study, we focused on the synovium and cartilage around the patellofemoral joint in patients with end-stage knee OA, and investigated the relationship between the SOD activities in these tissues at the same site.
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