Abstract
MXene has attracted tremendous attention due to its outstanding photothermal properties and biocompatibility. Hydroxyapatite (HA) contains Ca, Mg and P elements, which play important roles in promoting osteogenic differentiation of mesenchymal stem cells (MSCs). In this study, a class of composite nanofibers consisting of MXene nanosheets and HA nanoparticles (M-@HA NFs) are developed based on the synergistic effect of photothermal performance and osteogenic properties. The obtained composite nanofibers demonstrated excellent photothermal properties, and the temperature reached 44 °C under NIR exposure (808 nm). In addition, the composite nanofibers also displayed good biocompatibility and promote the growth and osteogenic differentiation of bone mesenchymal stem cells (BMSCs). More importantly, under NIR exposure, BMSCs on the composite nanofibers achieved much better osteogenic differentiation than those without NIR exposure due to the accelerated release of Ca, Mg and P elements. Therefore, we considered the unique photothermal and osteogenic differentiation to indicate that this new class of MXene composite nanofibers has tremendous application potential in bone tissue engineering.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
