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Abstract
Pathogenic bacteria that develop multidrug resistance pose extensive health hazards. TiO2 nanoparticles (NPs) generally show strong antibacterial activity under irradiation. Hence, we have analyzed the bactericidal efficiency of TiO2 in the absence of photo-activation by doping and co-doping MgO NPs, Ag NPs to anatase TiO2 NPs. Co-doped TiO2 (TAM) showed a high inhibition zone of 20mm and14mm against Escherichia coli and Bacillus subtilis respectively with reduced band gap energy of 3.27eV. Undoped TiO2 (TU), Ag NPs doped TiO2 (TA), MgO doped TiO2 (TM) showed particle sizes of 95nm, 35nm, 45nm respectively. Smaller particle size of 33nm observed in TAM combined with the synergistic effects of ROS formation effected by MgO and bactericidal Ag+ ions account for the bacterial inhibition.
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