Abstract
The research article presents the synthesis, characterization, and biological evaluation of amoxicillin functionalized with AgNPs with low toxicity and good antimicrobial property which can be produced with silver nitrate and amoxicillin drug in an environmentally friendly method. The synthesized nanoparticles were subjected to characterization by UV-visible spectroscopy, Fourier transform infrared spectroscopy, x-ray diffraction, field-emission scanning electron microscopy, and atomic force microscopy. The biological evaluation was carried out with the help of agar well diffusion using E. coli, minimum inhibitory concentration, DPPH radical scavenging assay, reducing power activity, total antioxidant activity, and anticancer activity of silver nanoparticles (AgNPs) against Hep-G2 cancer cell lines. The average particle size of the synthesized nanoparticles was 35.50 ± 0.23 nm. The drug release kinetics was carried out to analyze the release of amoxicillin from the AgNPs. The present study clearly establishes the synthesis and the application of amoxicillin functionalized silver nanoparticles to be utilized as an important tool to fight against antibiotic-resistant bacterial strains.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
