Syndrome of Inappropriate Secretion of Antidiuretic Hormone

Abstract

Comments1 December 1976Syndrome of Inappropriate Secretion of Antidiuretic HormoneJEFFREY BODACK, M.D.JEFFREY BODACK, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-85-6-829_3 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: In the recent paper by Vagenakis, Dole, and Braverman, "Pituitary Enlargement, Pituitary Failure, and Primary Hypothyroidism" (Ann Intern Med 85:195-198, 1976), the authors state that their second patient suffered from the inappropriate ADH syndrome (1), with sodium concentrations considerably below 130 meq/litre, elevated urine osmolality, and urine sodium in excess of 120 meq/litre. However, this patient's serum cortisols were undetectable, and his renal function was never clearly described.At our hospital, Dr. Albert, a nephrologist, states that adrenal function must be clearly delineated before the diagnosis of inappropriate ADH syndrome is made, as adrenocortical crisis might be...Reference1. BARTTERSCHWARTZ FW: The syndrome of inappropriate secretion of antidiuretic hormone. Am J Med 42:790-806, 1967 CrossrefMedlineGoogle Scholar1. AHMEDGEORGEAUVERT-GONZALES ABC: Increased plasma arginine vasosuppression in clinical adrenocortical insufficiency and its inhibition by glucosteroids. J Clin Invest 46:111, 1967 CrossrefMedlineGoogle Scholar2. AGUSGOLDBERG ZM: Role of antidiuretic hormone in the abnormal water diuresis of anterior hypopituitarism in man. J Clin Invest 50:1478, 1971 CrossrefMedlineGoogle Scholar3. SKOWSKYNIELSENFISHER RTD: Arginine vasosuppression kinetics in the thyroidectomized sheep. Program of the 56th Annual Meetings of the Endocrine Society, 1974 Google Scholar4. WILLIAMSROSEDLUHY GLR: Aldosterone response to sodium restriction and ACTH stimulation in panhypopituitarism. J Clin Endocrinol Metab 32:27, 1971 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Lankenau Hospital Philadelphia, PA 19151 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 December 1976Volume 85, Issue 6Page: 829-830KeywordsAntidiuretic hormoneAttentionCortisolHypothyroidismSodiumUrine Issue Published: 1 December 1976 PDF DownloadLoading ...