Abstract

Nine cases of pancytopenia and aplasia of the bone marrow following icteric hepatitis are presented, seven of which terminated fatally. An additional case of pancytopenia which probably followed anicteric hepatitis is also reported. The patients were mostly male and ranged in age from two to twenty years. The hepatitis in these cases is presumably viral, and the hematologic disorder may possibly result from viral induced chromosomal damage to the bone marrow. It is suggested that some cases of idiopathic aplastic anemia in children may be a sequel to anicteric hepatitis.

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