Syndrome dermorespiratoire : un phénotype sévère

Abstract

Atopic dermatitis is frequently the first step of the atopic march. Frequency and severity of subsequent asthma are higher in children with severe cutaneous lesions and with IgE-dependent multiple sensitisations. Filaggrin null mutations and food allergy are associated with increased severity of asthma. It remains to be demonstrated that treatment of atopic dermatitis will reduce the risk of subsequent allergic asthma and rhinitis.