Abstract

AbstractSince their discovery in 2013, anti-5’nucleotidase 1A (anti-cN1A) antibodies have been the subject of numerous publications to assess their sensitivity and diagnostic specificity. Currently used as an aid in the diagnosis of inclusion body myositis for which their specificity is good, they can be detected in other autoimmune diseases and in particular in Sjögren’s Syndrome. Their prevalence, which is significant during this disease, decreases diagnostic performance in patients with both myositis and Sjögren’s Syndrome. Anti-cN1A antibodies may also have a prognostic role during SGS.

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