Abstract
Clinical records and histiological materials of 21 patients with haemophagocytie syndrome classified as Class II by the histiocyte society were studied. Our results show that some different immune disorders (malignant disease, infection, immunodepression) alone or associated may lead to inappropriate activation of the mononuclear phagocyte system. Cytokine profile study could be helpful for diagnose and evolution of this often fatal disease
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