Abstract
Colorectal cancer (CRC) is the third most prevalent cancer in the world and is the second cause of cancer death. Positron emission tomography/computed tomography (PET/CT) using 18F-FDG is used for its staging and follow up. To assess the occurrence of synchronous colonic and extracolonic tumors detected with contrast-enhanced F18-FDG PET/CT (PET/CTc) in patients with a recently diagnosed CRC. PET/CTc of 210patients aged 16-91, years (63% men) with a recently diagnosed CRC were reviewed. PET/CTc with incidental findings, not expected to be due to CRC, were followed (laboratory, imaging and pathology) searching for synchronous tumors. Ten patients (4,7%) had a second synchronous CRC. Only 70% of synchronous CRC were accessible to colonoscopy, due mainly to incomplete procedures for stenotic tumors. Extracolonic synchronous neoplasms were detected in 12 patients (5,7%), namely lung cancer in three, renal cell carcinoma in two, non-Hodgkin lymphoma in two, pancreatic cancer in one, breast cancer in one, hepatocellular carcinoma in one, bladder cancer in one and thyroid cancer in one. Ten percent of patients with a recently diagnosed CRC had a synchronic neoplasm detected at staging using PET/CTc.
Highlights
Colorectal cancer (CRC) is the third most prevalent cancer in the world and is the second cause of cancer death
Aim: To assess the occurrence of synchronous colonic and extracolonic tumors detected with contrast-enhanced F18-FDG Positron emission tomography/computed tomography (PET/CT) (PET/CTc) in patients with a recently diagnosed CRC
Extracolonic synchronous neoplasms were detected in 12 patients (5,7%), namely lung cancer in three, renal cell carcinoma in two, non-Hodgkin lymphoma in two, pancreatic cancer in one, breast cancer in one, hepatocellular carcinoma in one, bladder cancer in one and thyroid cancer in one
Summary
Colorectal cancer (CRC) is the third most prevalent cancer in the world and is the second cause of cancer death. Aim: To assess the occurrence of synchronous colonic and extracolonic tumors detected with contrast-enhanced F18-FDG PET/CT (PET/CTc) in patients with a recently diagnosed CRC. Conclusions: Ten percent of patients with a recently diagnosed CRC had a synchronic neoplasm detected at staging using PET/CTc. Si bien se ha demostrado la mayor sensibilidad del PET/CT en detección de metástasis extrahepáticas respecto a la etapificación tradicional, y su significativo impacto en el manejo de pacientes oligometastásicos, encontrando siembra secundaria extrahepática en 25% de los pacientes con aparente metástasis única hepática, las guías aún no apoyan su uso extendido en etapificación de CCR, restringiéndose sólo a algunas situaciones, como pacientes oligometastásicos con opción de cirugía curativa que incluya metastasectomía, o en lesiones hepáticas o extrahepáticas dudosas con la TC y/o RM18. El objetivo de este estudio es determinar la frecuencia de tumores malignos sincrónicos colorrectales y extracolónicos en población con CCR que se realizó un PET/CTc de etapificación
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