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Abstract
Synchronous squamous cell carcinoma of the lung and type AB thymoma - is effective radical treatment possible?
Highlights
Secondary neoplasms occur in 8-31% of patients with primary thymic tumors and are mostly diagnosed after thymic cancer treatment
Thymectomy was selected before the thymic tumor histology had been established
The clinical stages of squamous cell carcinoma and thymoma were post-operatively determined as IIB and Masaoka-Koga III, respectively
Summary
Secondary neoplasms occur in 8-31% of patients with primary thymic tumors and are mostly diagnosed after thymic cancer treatment. A 71-year-old man with hypertension, type 2 diabetes, chronic obstructive pulmonary disease and long-term nicotinism was referred to us following incidental detection of a left-lung tumor on chest X-ray. Radiology suggested primary thymic and lung cancers and revealed no enlarged mediastinal nodes or other abnormalities. The pathological diagnosis was squamous cell lung carcinoma of pT3N0M0 stage (clinical stage IIB) due to parietal pleura involvement (Figure 2A) and type AB thymoma (Masaoka-Koga stage III due to microscopically confirmed mediastinal pleura infiltration) (Figure 2B). Based on the lung cancer stage, standard adjuvant chemotherapy was administered (cisplatin 80mg/m2 day 1, vinorelbine 30mg/m2 days 1, 8; every 21 days). Knetki-Wróblewska M (2019) Synchronous squamous cell carcinoma of the lung and type AB thymoma - is effective radical treatment possible?
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