Abstract
Synchronous primary ovarian and endometrial carcinomas is a rare condition encountured in clinical practice, especially in young patients with history of endometriosis. The most frequent histopatological subtype is endometrioid carcinoma. We present a case of a 36-years old patient admitted in the Emergency Department for lower abdominal pain and abnormal uterine bleeding. The clinical and ultrasound examination diagnosed bilateral ovarian cystic tumors, a normal uterine structure and no abdominal fluid colection. Serum levels of ROMA score was performed with normal value. The International Ovarian Tumor Analysis (IOTA) criteria used for ovarian tumors scoring diagnosed a 55% probability for malignant tumors. Laparotomy was performed with prelevation of peritoneal fluid for citology. After right anexectomy was performed, the intraoperative histopathological examination diagnosed endometrioid ovarian carcinoma. Left anexectomy and total hysterectomy with omentectomy and multiple peritoneal biopsy was further performed. The final histopathological examination confirmed endometroid carcinoma in both ovaries and endometrial tissue. Keywords: synchronous genital carcinomas, endometrioid subtype, endometriosis
Highlights
Recent literature shows that synchronous primary ovarian and endometrial carcinoma is the most frequent encountered diagnosis in case of synchronous reproductive genital tumours
Zaino et al [1] described that synchronous genital carcinomas were misdiagnosed as FIGO stage III - endometrial carcinoma or FIGO stage II - ovarian carcinoma
The histopathological criteria described by Scully et al [9] were used to differentiate between independent primary cancers and single malignant tumors associated with metastasis (Table 1)
Summary
CIPRIAN LAURENTIU PATRU1#, MARIUS CRISTIAN MARINAS2*#, ILEANA DROCAS1, FLORENTINA TANASE1, TIBERIU STEFANITA TENEA COJAN3#, GABRIEL FLORIN RAZVAN MOGOS3#, ANA MARIA IFRIM PREDOI3, VLAD DUMITRU BALEANU4#, DRAGOS VIRGIL DAVITOIU5#, RAZVAN-GRIGORAS CAPITANESCU1# 1University of Medicine and Pharmacy of Craiova, Obstetrics and Gynecology Department, 2 Petru Rares Str., 200349, Craiova, Romania 2University of Medicine and Pharmacy of Craiova, Anatomy Department, 2 Petru Rares Str., 200349, Craiova, Romania 3University of Medicine and Pharmacy of Craiova, General Surgery Department, 2 Petru Rares Str., 200349, Craiova, Romania 4University of Medicine and Pharmacy of Craiova, Surgery Department, Clinical Emergency Hospital St. We present a case of a 36-years old patient admitted in the Emergency Department for lower abdominal pain and abnormal uterine bleeding. The clinical and ultrasound examination diagnosed bilateral ovarian cystic tumors, a normal uterine structure and no abdominal fluid colection. After right anexectomy was performed, the intraoperative histopathological examination diagnosed endometrioid ovarian carcinoma. Coexisting carcinomas of the endometrium and ovaries were described in 10% of the ovarian and 5% of the endometrial tumors [1,2,3], the endometrioid carcinoma being most frequently reported. Experimental part This paper reports a case of a 36 years old patient hospitalized in the Obstetrics and Gynecology Department, Emergency County Hospital from Craiova, for pelvic pain and abnormal uterine bleeding.
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