Abstract
BackgroundAlthough uncommon, neoplasms of the appendix do exist. The two most common types are neuroendocrine tumors and mucinous appendiceal neoplasms. MethodsIn two patients unusual gross and microscopic findings in an appendectomy specimen were recorded. Special immunocytochemistry studies were used to determine the histologic type of the tumors in the appendix. ResultsThe clinical features and histopathology of two patients who had both a neuroendocrine tumor and a low grade appendiceal mucinous neoplasm in the same appendectomy specimen were described. Possibilities for the causation and treatment of this unusual condition were discussed. The incidence of this double malignancy was estimated at 2.5 in 1000 appendectomy specimens. ConclusionAlthough extremely unusual, a neuroendocrine tumor and a mucinous appendiceal neoplasm can exist in the same appendix. This condition is reported in two young patients.
Highlights
The most common pathology associated with the appendix is appendicitis
The incidence of appendiceal neoplasm is estimated at 1 % the incidence of colon and rectal cancer [3]
It is possible that the appendix, which is a tubular structure with a blind end, has a prolonged exposure to retained intestinal carcinogens
Summary
The two most common types are neuroendocrine tumors and mucinous appendiceal neoplasms. METHODS: In two patients unusual gross and microscopic findings in an appendectomy specimen were recorded. RESULTS: The clinical features and histopathology of two patients who had both a neuroendocrine tumor and a low grade appendiceal mucinous neoplasm in the same appendectomy specimen were described. Possibilities for the causation and treatment of this unusual condition were discussed. The incidence of this double malignancy was estimated at 2.5 in 1000 appendectomy specimens. CONCLUSION: extremely unusual, a neuroendocrine tumor and a mucinous appendiceal neoplasm can exist in the same appendix. This condition is reported in two young patients
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
