Abstract
IntroductionSynchronous double cancer of the gallbladder and pancreas that is associated with congenital biliary dilatation (CBD) and pancreaticobiliary maljunction (PBM) is extremely rare. PBM is frequently reported in Asia, particularly in Japan. We report a surgical case of synchronous double cancer in a patient with primary gallbladder and pancreatic cancer.Presentation of caseA 72-year-old woman with epigastralgia underwent subtotal stomach-preserving pancreaticoduodenectomy and gallbladder bed resection for synchronous primary gallbladder and pancreatic head cancer. Histopathological examination revealed moderately differentiated ductal adenocarcinoma of the pancreatic head and well-differentiated tubular adenocarcinoma at the bottom of the gallbladder.ConclusionSynchronous gallbladder and pancreatic cancer is extremely rare. It is necessary to determine the optimal surgical course taking into consideration the degree of tumor progression. This is the second case of synchronous primary gallbladder and pancreatic cancer associated with CBD accompanied by PBM.
Highlights
Synchronous double cancer of the gallbladder and pancreas that is associated with congenital biliary dilatation (CBD) and pancreaticobiliary maljunction (PBM) is extremely rare
The patient was diagnosed with synchronous primary gallbladder and intraductal papillary mucinous carcinoma (IPMC) because a 9-mm mural nodule was found in part of the cystic lesion by Computed tomography (CT)
BDC bile duct cancer, GBC gallbladder cancer, F female, M male, PC pancreatic cancer, PD pancreticoduodenectomy, SSPPD subtotal stomach-preserving pancreaticoduodenectomy, TP total pancreatectomy, CBD congenital biliary dilatation, PBM pancreaticobiliary maljunction that approximately one third of pancreatic cancers derived from intraductal papillary mucinous neoplasm (IPMN) are mucinous carcinoma, and most pancreatic cancers concomitant with IPMN are tubular adenocarcinoma, which are similar to ordinary pancreatic cancers
Summary
Synchronous gallbladder and pancreatic cancer is extremely rare. It is necessary to determine the optimal surgical course taking into consideration the degree of tumor progression.
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