Abstract
Multiple salivary gland tumors (MSGTs) can be classified by topographic distribution (unilateral or bilateral) and chronologic appearance (synchronous or metachronous). Oral presentation of these tumors is rare, and have been reported as either benign or malignant. To our knowledge, synchronous occurrence of adenoma and adenocarcinoma of minor salivary glands has not been reported in the literature. Herein we present a case of synchronous polymorphous low-grade adenocarcinoma (PLGA) and multifocal canalicular adenoma (CA) affecting a 61-year-old female patient who exhibited, in the oral examination, 9 discrete firm to fluctuant submucosal nodules (ranging from 0.2 to 0.8 cm in diameter) on the upper lip, with a 12-month evolution. The histopathologic analysis showed focal area containing PLGA and multiple CAs. After 1 year of follow-up, no recurrence was observed. After review of the English-language literature and different from our case, only 11 intraoral MSGTs (either benign or malignant) have been identified to date.
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