Synchronous invasive ductal breast cancer with clear cell renal carcinoma: a rare case report with review of literature

Abstract

Introduction: Multiple cancer refers to the emergence of 2 or more cancers in a single patient. This study aims to report a rare case of clear cell renal cancer associated with invasive breast ductal carcinoma. Case presentation: A 56-year-old female presented with a left breast mass. Clinical examination revealed a mobile left side breast mass at the left upper quadrant. An irregular hypoechoic mass was seen on ultrasound, and mammography showed a unifocal spiculated mass seated on the pectoralis muscle. Computed tomography of the chest and abdomen revealed a cystic mass lesion in the cortex of the lower pole of the left kidney. Partial nephrectomy and wide local breast mass excision with sentinel lymph node biopsy were done. Histopathologic results confirmed associated invasive ductal breast carcinoma with clear renal cell carcinoma. Discussion: In the treatment of renal cell carcinoma with multiple tumors, several factors should be interpreted, including the tumor stage, evaluation for the presence of metastasis, and whether the kidney tumor is accessible for operation. Conclusion: The term multiple cancer refers to the development of more than one tumor in a single patient that could be synchronous or metachronous. The association of invasive ductal breast cancer with clear renal cell carcinoma is a sparse entity.