Abstract

Synchronous double primary cancer of esophageal carcinoma and hepatocellular carcinoma is rare from the literature review. The incidence of intraepithelial squamous cell carcinoma of esophagus is also rare. Advanced HCC and esophageal carcinoma still have a dismal result despite modern management and suigical techniques. Small hepatocellular carcinoma and intraepithelial squamous cell carcinoma without lymph node metastasis usually show good prognosis. We report a 48-year-old male with chronic hepatitis B and alcoholism who developed alcohol withdrawal syndrome and Mallory-Weiss syndrome. Small hepatocellular carcinoma and intraepithelial squamous cell carcinoma of esophagus were found during hospitalization. Small hepatocellular carcinoma was first treated by percutaneous acetic acid injection and the intraepithelial squamous cell carcinoma of esophagus was managed by subtotal esophagectomy and reconstruction with gastric tube 2 months later. The patients felt essentially well up to 22 months after operation.

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