Synchronous Breast Carcinoma and Other Solid Malignancies: MDCT Evaluation

Abstract

Background and Objectives: The incidence of synchronous primary malignant tumors is increasing due to the ageing of the population and advances in medical technology. In this retrospective study; we review the multidetector computed tomography (MDCT) findings of synchronous breast carcinoma and other solid malignancies. Methods and Materials: This retrospective study included 65 patients confirmed with diagnosis of synchronous breast carcinoma and other solid malignancies. The patients aged ranged from 35 – 78 years. CT scanning was performed using 128 MDCT in all patients. All one hundred-thirty malignancies were underwent pathological evaluation. Results: Out of 4120 patients with breast carcinoma; 65 patients were diagnosed with other synchronous primary solid malignancy. All one hundred-thirty malignancies were confirmed pathologically. Breast carcinoma detected in all 65 patients; of them metastatic breast carcinoma detected in 8 patients. Hepatocellular carcinoma detected in 18 patients. Non-Hodgkin lymphoma (NHL) detected in 12 patients. Endometrial carcinoma detected in 8 patients. Uterine sarcoma detected in 3 patients. Malignant mixed Mullerian tumor detected in one patient. Ovarian carcinoma detected in 5 patients. Renal cell carcinoma detected in 4 patients. Thyroid carcinoma detected in 4 patients. Gastric carcinoma detected in 2 patients. Colonic carcinoma detected in 2 patients. Ano-rectal carcinoma detected in one patient. Hilar cholangiocarcinoma detected in 2 patients. Malignant melanoma detected in 2 patients. Bronchogenic carcinoma detected in one patient. Conclusions: Patients with breast carcinoma have a risk of other synchronous primary malignancy. So, careful preoperative examination is recommended to improve the patients’ prognosis. MDCT scanning is accurately imaging modality for evaluation of synchronous breast carcinoma and other solid malignancies. The aim of treatment in cancer patients should always be curative even in the presence of multiple malignancies. Funding Statement: There was no financial support for this research and publication. Declaration of Interests: The author declares that there is no conflict of interest. Ethics Approval Statement: The study was approved by the institutional research ethics review committee (Mansoura University/Faculty of Medicine/ Egypt). IRB reference number is “R.20.02.753