Abstract

A 30-year-old female patient was referred because of a tongue lesion with 3 months of evolution. Clinical oral examination revealed painful infiltrative ulcer in tongue dorsum measuring 3 × 2 cm with necrotic areas and well-defined limits. Biopsy was performed, and the histopathologic diagnosis was squamous cell carcinoma (SCC). The patient with clinical stage IV (T4aN1M0) cancer was treated with chemotherapy (CT) followed by partial glossectomy associated with unilateral supraomohyoid cervical emptying besides CT and radiotherapy post surgery. During treatment, her 28-year-old brother noticed a tongue lesion and sought care in our center. Clinical examination revealed a painless ulcer on right lateral tongue border measuring 2 × 1 cm with well-defined limits and rough surface. The histopathologic diagnosis was also SCC. The clinical stage I (T1N0M0) cancer led to tumor excision with margin control as the treatment. Currently, both siblings are being followed up at our center. A 30-year-old female patient was referred because of a tongue lesion with 3 months of evolution. Clinical oral examination revealed painful infiltrative ulcer in tongue dorsum measuring 3 × 2 cm with necrotic areas and well-defined limits. Biopsy was performed, and the histopathologic diagnosis was squamous cell carcinoma (SCC). The patient with clinical stage IV (T4aN1M0) cancer was treated with chemotherapy (CT) followed by partial glossectomy associated with unilateral supraomohyoid cervical emptying besides CT and radiotherapy post surgery. During treatment, her 28-year-old brother noticed a tongue lesion and sought care in our center. Clinical examination revealed a painless ulcer on right lateral tongue border measuring 2 × 1 cm with well-defined limits and rough surface. The histopathologic diagnosis was also SCC. The clinical stage I (T1N0M0) cancer led to tumor excision with margin control as the treatment. Currently, both siblings are being followed up at our center.

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