SYNBIOCHEM-a SynBio foundry for the biosynthesis and sustainable production of fine and speciality chemicals.

Pablo Carbonell,Jean-Loup Faulon,Rainer Breitling,Jason Micklefield,Alan Williams,Eriko Takano,Royston Goodacre,Philip Shapira,Carole Goble,Andrew Currin,Donal Fellows,Cunyu Yan,Neil Swainston,Christopher J Robinson ,Rosalind Le Feuvre ,George Guo-Qiang Chen ,Mark S Dunstan ,Douglas B Kell ,Perdita E Barran ,Adrian J Jervis ,Nigel S Scrutton ,Nicholas J W Rattray ,María Vinaixa ,Nicholas J Turner

doi:10.1042/bst20160009

Abstract

The Manchester Synthetic Biology Research Centre (SYNBIOCHEM) is a foundry for the biosynthesis and sustainable production of fine and speciality chemicals. The Centre's integrated technology platforms provide a unique capability to facilitate predictable engineering of microbial bio-factories for chemicals production. An overview of these capabilities is described.

Highlights

The Manchester University Synthetic Biology Research Centre (SBRC), SYNBIOCHEM, is focused on delivering Synthetic Biology (SynBio) solutions that provide innovative, fast, predictable and robust production routes for diverse fine and speciality chemicals underpinned by Responsible Research and Innovation (RRI)
SYNBIOCHEM is located in the Manchester Institute of Biotechnology (MIB; http://www.mib.ac.uk/) and builds on the MIB’s core strategy of uniting teams of interdisciplinary scientists and industrial partners to deliver challenge-led innovation in bio-based chemicals and broader industrial
SYNBIOCHEM builds on a long-term vision and commitment by the University of Manchester in sustainable Industrial Biotechnology, leveraging and integrating world-leading capabilities in MIB Centres of Excellence including: Biocatalysis, Biotransformation and Biocatalytic Manufacture (CoEBio3); Manchester Centre for Biophysics and Catalysis (MCBC); Manchester Centre for Integrative Systems Biology (MCISB) and the Michael Barber Collaborative Centre for MS (MBCMS)

Summary

Introduction

The Manchester University Synthetic Biology Research Centre (SBRC), SYNBIOCHEM (http://synbiochem. co.uk), is focused on delivering Synthetic Biology (SynBio) solutions that provide innovative, fast, predictable and robust production routes for diverse fine and speciality chemicals underpinned by Responsible Research and Innovation (RRI). SYNBIOCHEM is located in the Manchester Institute of Biotechnology (MIB; http://www.mib.ac.uk/) and builds on the MIB’s core strategy of uniting teams of interdisciplinary scientists and industrial partners to deliver challenge-led innovation in bio-based chemicals and broader industrial

Results

Conclusion