Abstract
SynBioBrain: building biological computers from bacterial Using synthetic biology, we can now engineer bacteria into whole-cell biosensors where sensing, transduction and output occur within the living cell. Applications include the detection of harmful environmental agents, bioprocess monitoring, and detecting medically relevant biomarkers. Engineering microbial consortia allows biosensor information to be integrated and processed in a distributed fashion. In this project, we construct biological computers formed from engineered bacterial populations that communicate using intercellular signalling molecules. Our approach opens up new ways to perform biological computation.
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