Abstract
Experimental evidence has shown that in some neuron types, such as hippocampal CA1 neurons, distally generated excitatory postsynaptic potentials (EPSPs) are scaled up in amplitude compared to more proximally generated EPSPs such that EPSP magnitudes at the soma are approximately equal regardless of the dendritic location of origin. Using an equivalent cable model neuron, we show that a particular form of spike-timing dependent plasticity (STDP) called anti-STDP is capable of achieving this synaptic equalization. Anti-STDP equalizes synapses through the equalization of synaptic efficacies. We show this result for both a passive dendritic cable and for a cable containing a dendritic spike-initiation zone.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
