Abstract
1. Forty six women presenting with symptoms of premenstrual syndrome (PMS) were studied. Ages ranged from 21 to 32. All women answered a questionnaire based on DSM-III-R criteria. They then had serum β-endorphin levels drawn on day 1 and day 20 of their menstrual Cycle. 2. Beta-endorphin levels were compared with symptom presentation. Such symptoms as anxiety, food cravings and physicial discomfort were associated with significant decline In β -endorphin. Other symptoms were found equally distributed in both groups. The existence or absence of β-endorphin decline in specific PMS subgroup was postulated.
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