Abstract
Aim of the studyThe aim of the study was to investigate the correlation between symptoms of overactive bladder (OAB) and severity of depressive symptoms in patients treated for depression.Subject or material and methods102 patients (43 m, 59 f) aged 20–67 (M = 46.1±11,3) treated for depression were included. OAB symptoms were examined with the International Prostate Symptom Score (IPSS) and International Consultation on Incontinence Questionnaire Overactive Bladder Module (ICIQ-OAB). OAB-related quality of life - with the International Consultation on Incontinence Questionnaire Overactive Bladder Quality of Life Module (ICIQ-OABqol). Depressive symptoms - with the 17-item Hamilton Depression Rating Scale (HDRS) and Quick Inventory of Depressive Symptomatology – Self Report (QIDS-SR).ResultsSymptoms of OAB were more severe in women than in men. In the entire group highest scores in IPSS of assessed OAB symptoms were observed in nocturia, followed by urinary frequency and lowest in urgency. Symptoms of OAB were more bothersome in women, than in men. Patients suffering from at least moderate depression assessed with QIDS-SR had significantly more pronounced symptoms of urinary frequency and urgency. A number of other significant correlations were observed.DiscussionOAB symptoms are common among patients treated for depressive disorders. There is a correlation between severity of depressive symptoms and OAB. OAB is bothersome and affects the quality of life in patients treated for depression.ConclusionsComorbidity of OAB and depression has clinical significance and that should enhance interdisciplinary treatment approaches. Due to limitations of this study, further researches are essential to reveal more details of the correlation between OAB and depression.
Highlights
IntroductionOveractive Bladder (OAB) refers to, according to International Continence Society (ICS) definition from 2002, the occurrence of urinary urgency usually accompanied by pollakiuria (urination 8 or more times a day, or according to recent diagnostic trends such frequency, which is associated with annoyance and a decrease in quality of life) and nokturia (the complaint that the individual has to wake at night one or more times for voiding and urinating is preceded by a period of sleep, which follows), with a possible urine incontinence [1].The above symptoms belong to the lower urinary tract symptoms (LUTS), and to the LUTS related to urinary accumulation [1]
Overactive Bladder (OAB) refers to, according to International Continence Society (ICS) definition from 2002, the occurrence of urinary urgency usually accompanied by pollakiuria and nokturia, with a possible urine incontinence [1].The above symptoms belong to the lower urinary tract symptoms (LUTS), and to the LUTS related to urinary accumulation [1]
Symptoms of OAB assessed with International Prostate Symptom Score (IPSS) and ICIQ-OAB were more severe in women than in men
Summary
Overactive Bladder (OAB) refers to, according to International Continence Society (ICS) definition from 2002, the occurrence of urinary urgency usually accompanied by pollakiuria (urination 8 or more times a day, or according to recent diagnostic trends such frequency, which is associated with annoyance and a decrease in quality of life) and nokturia (the complaint that the individual has to wake at night one or more times for voiding and urinating is preceded by a period of sleep, which follows), with a possible urine incontinence [1].The above symptoms belong to the lower urinary tract symptoms (LUTS), and to the LUTS related to urinary accumulation [1]. The diagnosis of OAB, based on collecting the accurate patient’ medical record and physical examination, requires exclusion of urinary tract infection and other urinary tract pathologies. In multicentre studies carried out up to now, on large groups representative of the general population, the incidence of OAB was 9-43% in the examined women and 7-27% in men [2,3,4,5,6]. The incidence of OAB symptoms increases with age, both in women and in men [5,6]
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