Abstract

Traditionally, Star Anise has been used as an antispasmodic in the form of home infusions for the treatment of newborn colic. The objective of this study was to identify the most frequent symptoms of intoxication due to the administration of star anise infusion in pediatric patients. A literature search was performed to identify published reports regarding star anise poisoning in the MEDLINE, PubMed, and Google Scholar databases. 137 cases of star anise intoxication were detected for the period 2014-2019 in which it was found that star anise intoxication has neurotoxic, hepatotoxic, gastrointestinal toxicity and inducer of hypersensitivity reactions.

Highlights

  • The Illicium verum is a shrub belonging to the Illiciaceae family, it is native to the southwest of China, it is called French anise, Chinese badian, Chinese anise and star anise. 1 It can reach 5 meters in height, its leaves are spearheadshaped, its flowers are yellowish-green with 15 to 20 spiral-shaped petals, the fruits are reddish-brown in color that are formed between six to eleven follicles

  • In the Google Scholar search engine, the phrases used were: "pediatric star anise intoxication" "star anise intoxication in children" "star anise intoxication". 3 long articles were obtained on the subject, while in the Google search engine 2 articles were located in the 2008-2019 interval

  • According to the literature review, it was found that star anise intoxication has neurotoxic, hepatotoxic, gastrointestinal toxicity and inducer of hypersensitivity reactions (Table 1)

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Summary

Introduction

The Illicium verum is a shrub belonging to the Illiciaceae family, it is native to the southwest of China, it is called French anise, Chinese badian, Chinese anise and star anise. 1 It can reach 5 meters in height, its leaves are spearheadshaped, its flowers are yellowish-green with 15 to 20 spiral-shaped petals, the fruits are reddish-brown in color that are formed between six to eleven follicles. 1 It can reach 5 meters in height, its leaves are spearheadshaped, its flowers are yellowish-green with 15 to 20 spiral-shaped petals, the fruits are reddish-brown in color that are formed between six to eleven follicles. They have a pointed end, are found around a central petiole, resembling a star, inside there is an ovoid seed. The knowledge about this plant spread throughout Europe and Asia, as well as its use for therapeutic purposes Dioscorides already records it from the 1st century AD, in his great work De Materia Medica, a treatise on plants with therapeutic uses. A preparation of leaves and seeds in tea is recommended to remove abdominal pain, eliminate intestinal gas and improve digestion and appetite

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